
MESCALINE
PEYOTE, SAN PEDRO
3,4,5-TRIMETHOXYPHENETHYLAMINE
All information sourced from DanceSafe.org
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WHAT IS MESCALINE?
- HOW IS MESCALINE USED?
- WHAT ARE THE EFFECTS OF MESCALINE?
- WHAT IS THE DOSAGE OF MESCALINE?
- HARM REDUCTION TIPS FOR MESCALINE.
WHAT IS MESCALINE?
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Mescaline is a natural psychedelic and is the psychoactive substance found in peyote and San Pedro cacti.
- Nearly 80% of the Peyote Cactus is underground with only the grayish-green pincushion-like top appearing above the ground (this top is called ‘the button’).
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WHAT IS MESCALINE?
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Mescaline was first isolated from peyote near the end of the 19th century and has a history of use in Central America dating back thousands of years.
- Multiple religious organization use Peyote as a sacramental part of their religion, including the Peyote Way Church and The Native American Church.
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HOW IS
MESCALINE USED?
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Peyote, also known as “mescalito”,
is usually orally consumed in pairs
of “buttons.”
- Cacti containing Mescaline have
also been used in the form of a tea.
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HOW IS
MESCALINE USED?
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Although rare, mescaline can be found in “underground markets” in synthetic and extracted crystalline form. Many times drugs from the 2C family will be misrepresented as ‘synthetic mescaline’.
- A single dose of crystal mescaline is nearly half a gram of powder. If a smaller amount than this is being sold as ‘synthetic mescaline’, it is likely a misrepresented research chemical.
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WHAT ARE THE EFFECTS OF MESCALINE?
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The effects of Mescaline are similar to those found in LSD with an increase in heart rate, blood pressure, and body temperature. Pupil dilation also occurs when taking a dose of mescaline.
• The perception of vivid colors and other visual effects often occur.
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WHAT ARE THE EFFECTS OF MESCALINE?
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Tolerance with mescaline develops slower in comparison to LSD and other psychedelics.
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Many people report an increase in sociability with others.
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Onset of mescaline effects ranges from 45 to 60 minutes, the peak lasts for around 4 hours, and the come down duration is from 4 to 8 hours.
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WHAT IS THE DOSAGE
OF MESCALINE?
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A standard oral dose of mescaline ranges from 400 mg to 600 mg.
- A general rule of thumb is 2 peyote buttons or
one foot of San Pedro per dose.
- Myths of mescaline being available in micro dot form are false due to amount of mescaline needed in order to feel its effects.
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HARM REDUCTION
TIPS FOR MESCALINE
- As with all psychedelics, ‘set’ and ‘setting’ are extremely important. "Set" is the mental state a person brings to the experience - their thoughts, mood and expectations. "Setting" is the physical and social environment in which the drug is being consumed.
By making sure that a person is in a good mental state and supportive location before mescaline is used, the risk of ‘bad trips’ can be greatly mitigated.
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HARM REDUCTION
TIPS FOR MESCALINE
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Mescaline is illegal and is listed as a
Schedule I drug.
Negative effects include being “violently sick” for up to 24 hours and the taste of all forms of mescaline (even pure mescaline) is reported as “hard to swallow.”
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